An Analysis of the Phytochemical Properties and Antimicrobial Activity of Aloe barbadensis on Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa

Event Type

Research Presentation

Academic Department

Chemistry, Biology

Location

Dana Science Building, 2nd floor

Start Date

24-4-2026 1:00 PM

End Date

24-4-2026 2:30 PM

Description

The purpose of this study was to investigate the antimicrobial properties of different parts of the aloe plant. Specifically, we examined how aloe gel, latex, and leaves affected the growth of pathogens: Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa. We analyzed the chemical composition of each aloe component using high performance liquid chromatography. Using a disk diffusion assay, the gel, latex, and rind extracts, along with control and standard solutions were tested for their antibacterial efficacy against three ESKAPE pathogens: S. aureus, K. pneumoniae, and P. aeruginosa. The aloe components showed no inhibition of bacterial growth, while the antibiotics used as positive controls were effective. These findings suggest that further investigation of the aloe components is warranted.

Comments

Under the direction of Dr. Mary Jane Carmichael, Dr. Daniel R. Derringer, and Dr. Molly Weselcouch.

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Apr 24th, 1:00 PM Apr 24th, 2:30 PM

An Analysis of the Phytochemical Properties and Antimicrobial Activity of Aloe barbadensis on Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa

Dana Science Building, 2nd floor

The purpose of this study was to investigate the antimicrobial properties of different parts of the aloe plant. Specifically, we examined how aloe gel, latex, and leaves affected the growth of pathogens: Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa. We analyzed the chemical composition of each aloe component using high performance liquid chromatography. Using a disk diffusion assay, the gel, latex, and rind extracts, along with control and standard solutions were tested for their antibacterial efficacy against three ESKAPE pathogens: S. aureus, K. pneumoniae, and P. aeruginosa. The aloe components showed no inhibition of bacterial growth, while the antibiotics used as positive controls were effective. These findings suggest that further investigation of the aloe components is warranted.