Event Title

Psychological and Chemical Processes

Start Date

8-5-2021 3:20 PM

End Date

8-5-2021 4:05 PM

Description

Psychological and Chemical Processes (speakers in order of appearance)

Maria Jdid '21 “Synthesis and Evaluation of the Rhodamine- and Biotin-Probes for Detection of Cysteine Containing Proteins” (Faculty Sponsor: Son Nguyen)

Along with glutathione, the biological thiol cysteine (Cys) plays important roles in many biological processes such as cellular detoxification and metabolism in living organisms. Changes in intracellular Cys concentration have profound effects on these biological processes. Given the critical importance of Cys homeostasis in biological systems, a strong interest has emerged in developing effective probes to detect and image Cys-rich proteins. This presentation focuses on the synthesis and evaluation of probes which are used to labeled Cys-rich proteins in biological systems, especially in redox systems, and in some diseases. Future examination will aim to understand the functions and activities of these proteins in some specific diseases.

Mary Rash '21 “C-Glycosylation Through Reductive Halide Atom-Transfer Reaction with Photo-irradiation” (Faculty Sponsor: Son Nguyen)

The central theme of this presentation focuses on developing a new C-glycosylation method via reductive halide atom transfer with photo-irradiation with high stereoselectivity and yield and understanding the mechanism of the method. Unlike previous radical glycosylation methods, this one does not use a chemical radical initiator but is carried out under irradiation using a low-pressure Hg lamp. The scope of reaction with a number of different donor/acceptor pairs will be studied. Mechanistic study of these methods will provide valuable insight into the factors that help to improve the efficiency of the reaction as well as stereoselectivity. This method will be applied in the total synthesis of some valuable natural products containing C-glycosidic bonds.

Apoorva Verma '22 “Are Grandiose and Vulnerable Narcissism Associated with Social Media Use?” (Faculty Sponsor: Bonnie Bowers)

Narcissism has been linked with various maladaptive behaviors, especially on social media. However, previous literature has relied on measures of grandiose narcissism. To close the gap, the present study examines the relationship between grandiose and vulnerable narcissists and their online-self presentation on Instagram. Keeping in mind its complexity, the construct of grandiose narcissism was further divided into its adaptive and maladaptive sub-parts. Online self-presentation on Instagram was assessed through individuals' overall self-presentation behaviors, their deliberation over the photos they post on Instagram, the authenticity of their self-presentation, and the depth of their self-presentation. A Qualtrics survey was conducted on 63 participants recruited from Hollins University. Spearman rho correlations revealed that grandiose narcissism was positively associated with the depth of online presentations and deliberate photo selection, whereas vulnerable narcissism was positively associated with overall self-presentation. Moreover, the rivalry subset of grandiose narcissism, but not overall grandiose narcissism or the admiration subset of narcissism, was negatively associated with the authenticity of self-presentation. Therefore, both grandiose and vulnerable narcissists tend to engage in self-promotional behaviors on Instagram. This study also shed light on the relevance of specific social media platforms as moderators of narcissism-social media relationships.

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May 8th, 3:20 PM May 8th, 4:05 PM

Psychological and Chemical Processes

https://hollins.zoom.us/webinar/register/WN_POZz8UWdSTOMNFh58Vv6fg

Psychological and Chemical Processes (speakers in order of appearance)

Maria Jdid '21 “Synthesis and Evaluation of the Rhodamine- and Biotin-Probes for Detection of Cysteine Containing Proteins” (Faculty Sponsor: Son Nguyen)

Along with glutathione, the biological thiol cysteine (Cys) plays important roles in many biological processes such as cellular detoxification and metabolism in living organisms. Changes in intracellular Cys concentration have profound effects on these biological processes. Given the critical importance of Cys homeostasis in biological systems, a strong interest has emerged in developing effective probes to detect and image Cys-rich proteins. This presentation focuses on the synthesis and evaluation of probes which are used to labeled Cys-rich proteins in biological systems, especially in redox systems, and in some diseases. Future examination will aim to understand the functions and activities of these proteins in some specific diseases.

Mary Rash '21 “C-Glycosylation Through Reductive Halide Atom-Transfer Reaction with Photo-irradiation” (Faculty Sponsor: Son Nguyen)

The central theme of this presentation focuses on developing a new C-glycosylation method via reductive halide atom transfer with photo-irradiation with high stereoselectivity and yield and understanding the mechanism of the method. Unlike previous radical glycosylation methods, this one does not use a chemical radical initiator but is carried out under irradiation using a low-pressure Hg lamp. The scope of reaction with a number of different donor/acceptor pairs will be studied. Mechanistic study of these methods will provide valuable insight into the factors that help to improve the efficiency of the reaction as well as stereoselectivity. This method will be applied in the total synthesis of some valuable natural products containing C-glycosidic bonds.

Apoorva Verma '22 “Are Grandiose and Vulnerable Narcissism Associated with Social Media Use?” (Faculty Sponsor: Bonnie Bowers)

Narcissism has been linked with various maladaptive behaviors, especially on social media. However, previous literature has relied on measures of grandiose narcissism. To close the gap, the present study examines the relationship between grandiose and vulnerable narcissists and their online-self presentation on Instagram. Keeping in mind its complexity, the construct of grandiose narcissism was further divided into its adaptive and maladaptive sub-parts. Online self-presentation on Instagram was assessed through individuals' overall self-presentation behaviors, their deliberation over the photos they post on Instagram, the authenticity of their self-presentation, and the depth of their self-presentation. A Qualtrics survey was conducted on 63 participants recruited from Hollins University. Spearman rho correlations revealed that grandiose narcissism was positively associated with the depth of online presentations and deliberate photo selection, whereas vulnerable narcissism was positively associated with overall self-presentation. Moreover, the rivalry subset of grandiose narcissism, but not overall grandiose narcissism or the admiration subset of narcissism, was negatively associated with the authenticity of self-presentation. Therefore, both grandiose and vulnerable narcissists tend to engage in self-promotional behaviors on Instagram. This study also shed light on the relevance of specific social media platforms as moderators of narcissism-social media relationships.