Synthesis and evaluation of the rhodamine- and biotin- probes for detection of cysteine containing proteins
Event Type
Research Presentation
Academic Department
Chemistry
Location
Zoom: Pre-registration required
Event Website
https://hollins.zoom.us/webinar/register/WN_ACD9em_WQrSbk94ivF4bdw
Start Date
7-4-2021 6:30 PM
Description
Along with glutathione, biological thiol cysteine (Cys) plays important roles in many biological processes such as cellular detoxification and metabolism in living organisms. Changes in intracellular Cys concentration have a profound effect on these biological processes. Given the critical importance of Cys homeostasis in biological systems, a strong interest has emerged in developing effective probes to detect and image Cys-rich proteins. In this oral presentation, the synthesis and evaluation of probes which we are working on and would be used to label Cys-rich proteins in biological systems, especially in redox systems, will be presented.
Synthesis and evaluation of the rhodamine- and biotin- probes for detection of cysteine containing proteins
Zoom: Pre-registration required
Along with glutathione, biological thiol cysteine (Cys) plays important roles in many biological processes such as cellular detoxification and metabolism in living organisms. Changes in intracellular Cys concentration have a profound effect on these biological processes. Given the critical importance of Cys homeostasis in biological systems, a strong interest has emerged in developing effective probes to detect and image Cys-rich proteins. In this oral presentation, the synthesis and evaluation of probes which we are working on and would be used to label Cys-rich proteins in biological systems, especially in redox systems, will be presented.
https://digitalcommons.hollins.edu/science_seminar/2021/presentations/12
Comments
Under the direction of Dr. Son H. Nguyen.
Oral presentation; no poster provided.